{"product_id":"selection-bias-and-covariate-imbalances-in-randomized-clinical-trials-hardcover-1","title":"Selection Bias and Covariate Imbalances in Randomized Clinical Trials - Hardcover","description":"\u003cdiv\u003e\u003cp style=\"text-align: right;\"\u003e\u003ca href=\"https:\/\/reportcopyrightinfringement.com\/\" target=\"_blank\" rel=\"nofollow\"\u003e\u003cb\u003eReport copyright infringement\u003c\/b\u003e\u003c\/a\u003e\u003c\/p\u003e\u003c\/div\u003e\u003cp\u003eby \u003cb\u003eVance Berger\u003c\/b\u003e (Author)\u003c\/p\u003e\u003cp\u003eSelection bias can, and does, occur, even in randomized clinical trials. Steps need to be taken in order to ensure that this does not compromise the integrity of clinical trials; hence \"Selection Bias and Covariate Imbalances in Randomized Clinical Trials\" offers a comprehensive treatment of the subject and the methodology involved. This book: \u003c\/p\u003e\u003cul\u003e \u003cli\u003eProvides an overview of the hierarchy of study designs, and justifies the position of randomised trials at the top of this hierarchy.\u003c\/li\u003e \u003cli\u003eDiscusses the strengths and defects of randomisation, and provides real evidence to justify concern regarding its defects.\u003c\/li\u003e \u003cli\u003eOutlays the damaging consequences that selection bias causes when it does occur.\u003c\/li\u003e \u003cli\u003eConsiders courses of action that can be taken to manage\/ contain the problem.\u003c\/li\u003e \u003cli\u003ePresents methods that can be used to detect selection bias in randomised trials, and methods to correct for selection bias.\u003c\/li\u003e \u003cli\u003eConcludes by providing a comprehensive plan for managing baseline imbalances and selection bias in randomised trials, and proposing open problems for future research.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e Illustrated with case studies, this book introduces groundbreaking ideas and research that will be invaluable to researchers and practitioners who design and analyse clinical trials. It will also be of interest to graduate students within the field of biostatistics. \u003c\/p\u003e\u003ch3\u003eBack Jacket\u003c\/h3\u003e\u003cp\u003eBaseline data in clinical trials consists of information regarding patients that is measured at the outset, prior to randomization (or treatment with study medications). In studies where important baseline factors appear well balanced, it can be reasonably concluded that any differences in outcome between the intervention and control groups are a real effect of treatment. The common assumption that any baseline differences in a randomized study are necessarily random is, however, misplaced. Selection bias can, and does, occur - even in randomized clinical trials. Steps need to be taken in order to ensure that this does not compromise the integrity of clinical trials; hence \u003ci\u003eSelection Bias and Covariate Imbalances in Randomized Clinical Trials\u003c\/i\u003e offers the first comprehensive treatment of the subject and the methodology involved. \u003c\/p\u003e\u003cul\u003e \u003cli\u003eProvides an overview of the hierarchy of study designs, and justifies the position of randomized trials at the top of this hierarchy.\u003c\/li\u003e \u003cli\u003eDiscusses the strengths and defects of randomization, and provides real evidence to justify concern regarding its defects.\u003c\/li\u003e \u003cli\u003eOutlays the damaging consequences that selection bias causes when it does occur.\u003c\/li\u003e \u003cli\u003eConsiders courses of action that can be taken to manage\/contain the problem.\u003c\/li\u003e \u003cli\u003ePresents methods that can be used to detect selection bias in randomized trials, and methods to correct for selection bias.\u003c\/li\u003e \u003cli\u003eConcludes by providing a comprehensive plan for managing baseline imbalances and selection bias in randomized trials, and proposing open problems for future research.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eSelection Bias and Covariate Imbalances in Randomized Clinical Trials\u003c\/i\u003e provides an in-depth overview of a key aspect in the design and analysis of clinical trials, featuring modern and novel approaches to the methodology described. Illustrated with case studies, this book introduces groundbreaking ideas and research that will be invaluable to researchers and practitioners who design and analyse clinical trials. It will also be of interest to graduate students within the field of biostatistics.\u003c\/p\u003e\u003ch3\u003eAuthor Biography\u003c\/h3\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eVance Berger is the author of Selection Bias and Covariate Imbalances in Randomized Clinical Trials, published by Wiley.\u003c\/p\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 224\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 0.69 x 9.26 x 6.08 IN\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eIllustrated:\u003c\/strong\u003e Yes\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e June 01, 2005\u003c\/div\u003e\n            ","brand":"BooksCloud","offers":[{"title":"Default Title","offer_id":53043100549427,"sku":"9780470863626","price":146.61,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0300\/5595\/6612\/files\/xBL8bxttmU9780470863626_7eb79287-6519-44d1-b9ea-a48a6466d509.webp?v=1770840561","url":"https:\/\/www.vysn.com\/products\/selection-bias-and-covariate-imbalances-in-randomized-clinical-trials-hardcover-1","provider":"VYSN","version":"1.0","type":"link"}