{"product_id":"dynamic-force-spectroscopy-and-biomolecular-recognition-paperback","title":"Dynamic Force Spectroscopy and Biomolecular Recognition - Paperback","description":"\u003cdiv\u003e\u003cp style=\"text-align: right;\"\u003e\u003ca href=\"https:\/\/reportcopyrightinfringement.com\/\" target=\"_blank\" rel=\"nofollow\"\u003e\u003cb\u003eReport copyright infringement\u003c\/b\u003e\u003c\/a\u003e\u003c\/p\u003e\u003c\/div\u003e\u003cp\u003eby \u003cb\u003eAnna Rita Bizzarri\u003c\/b\u003e (Editor), \u003cb\u003eSalvatore Cannistraro\u003c\/b\u003e (Editor)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eMolecular recognition, also known as biorecognition, is the heart of all biological interactions. Originating from protein stretching experiments, dynamic force spectroscopy (DFS) allows for the extraction of detailed information on the unbinding process of biomolecular complexes. It is becoming progressively more important in biochemical studies and is finding wider applications in areas such as biophysics and polymer science. In six chapters, \u003cstrong\u003eDynamic Force Spectroscopy and Biomolecular Recognition\u003c\/strong\u003e covers the most recent ideas and advances in the field of DFS applied to biorecognition: \u003c\/p\u003e\u003cul\u003e \u003cp\u003e \u003c\/p\u003e \u003cli\u003e \u003cem\u003eChapter 1: \u003c\/em\u003e Reviews the basic and novel aspects of biorecognition and discusses the emerging capabilities of single-molecule techniques to disclose kinetic properties and molecular mechanisms usually hidden in bulk measurements\u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 2: \u003c\/em\u003e Describes the basic principle of atomic force microsocopy (AFM) and DFS, with particular attention to instrumental and theoretical aspects more strictly related to the study of biomolecules\u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 3: \u003c\/em\u003e Overviews the theoretical background in which experimental data taken in nonequilibrum measurements of biomolecular unbinding forces are extrapolated to equilibrium conditions\u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 4: \u003c\/em\u003e Reviews the most common and efficient strategies adopted in DFS experiments to immobilize the interacting biomolecules to the AFM tip and to the substrate\u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 5: \u003c\/em\u003e Presents and discusses the most representative aspects related to the analysis of DFS data and the challenges of integrating well-defined criteria to calibrate data in automatic routinary procedures \u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 6\u003c\/em\u003e\u003cstrong\u003e: \u003c\/strong\u003e Overviews the most relevant DFS applications to study biorecognition processes, including the biotin\/avidin pair, and selected results on various biological complexes, including antigen\/antibody, proteins\/DNA, and complexes involved in adhesion processes \u003c\/li\u003e \u003cli\u003e \u003cem\u003eChapter 7\u003c\/em\u003e\u003cstrong\u003e: \u003c\/strong\u003e Summarizes the main results obtained by DFS applied to study biorecognition processes with forthcoming theoretical and experimental advances\u003c\/li\u003e \u003c\/ul\u003e\u003cp\u003eAlthough DFS is a widespread, worldwide technique, no books focused on this subject have been available until now. \u003cstrong\u003eDynamic\u003c\/strong\u003e \u003cstrong\u003eForce Spectroscopy and Biomolecular Recognition\u003c\/strong\u003e provides the state of the art of experimental data analysis and theoretical procedures, making it a useful tool for researchers applying DFS to study biorecognition processes.\u003c\/p\u003e\u003ch3\u003eAuthor Biography\u003c\/h3\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAnna Rita Bizzarri\u003c\/strong\u003e received her degree in Physics in 1987 from the University of Rome. She obtained the Ph.D. in Biophysics in 1992 from SISSA in Trieste. After postdoctoral fellowships in Perugia and Mainz she joined the Science Faculty at Tuscia University, Italy, as research assistant. In 2000, she became Associate Professor of Physics and in 2006 she got the position of full Professor. Her scientific interests include spectroscopic investigations and MD simulations of electron transfer metalloproteins. More recently, she has focused on single-molecule level detection by surface enhanced Raman spectroscopy and scanning probe microscopies for both fundamental and applicative aims.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eSalvatore Cannistraro \u003c\/strong\u003eobtained his degree in Physics in 1972 from Pisa University. He received his Ph.D. in Biophysics at Liegi University, Belgium. In 1977, he became reader of Biophysics at Calabria University. He moved to Perugia University in 1981 as Associate Professor of Molecular Physics. Since 1991, he has been a full professor of Physics, Biophysics, and Nanoscience at Tuscia University, leading the Biophysics and Nanoscience Centre. His scientific interests include optical, magnetic, neutron spectroscopies and modelling of amorphous and biological systems. More recently, he is focusing his activity on the application of AFM, STM, and Raman SERS to single biomolecule detection and nanobiomedicine.\u003c\/p\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 288\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 0.6 x 9.21 x 6.14 IN\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eIllustrated:\u003c\/strong\u003e Yes\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e November 21, 2018\u003c\/div\u003e\n            ","brand":"BooksCloud","offers":[{"title":"Default Title","offer_id":54053471355187,"sku":"9781138374522","price":156.02,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0300\/5595\/6612\/files\/6PFLJ9AJPy9781138374522.webp?v=1789019971","url":"https:\/\/www.vysn.com\/products\/dynamic-force-spectroscopy-and-biomolecular-recognition-paperback","provider":"VYSN","version":"1.0","type":"link"}